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    Sustained oxygen-releasing hydrogel implants enhance flap regeneration by promoting mitochondrial biogenesis under mild hypoxia

    Sustained oxygen-releasing hydrogel implants enhance flap regeneration by promoting mitochondrial biogenesis under mild hypoxia by Sungmi Jeon, Seol-Ha Jeong, Mi Hyun Lee, Jeong Wook Seo, Da-Seul Kim, Nicole Joy Bassous, Javier Alejandro Lozano Soto, Cholong Choi, Montserrat Legorreta Gonzalez, Elaine Belén Nolasco Díaz, Hyunho Kim, Su Ryon Shin, Ji-Ung Park

    Published 2025-09-01

    In regenerative medicine, effective management of tissue ischemia in surgical skin flaps is crucial, yet challenging, particularly because inadequate blood flow often leads to necrosis at the distal flap tips. This study aimed to examine the therapeutic potential of catalase-coated oxygen-generating...

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