Search Results - D. L. Shukevich

Despite the availability of modern drugs, examination and treatment methods, the issue of cognitive dysfunction is still fairly important for intensive care and anaesthesiologic practice. The review presents statistic data on the frequency of cognitive dysfunction, discusses main tests used for dete...

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Purpose of the study: to evaluate the organoprotective effects of veno-arterial extracorporeal membrane oxygenation and intra-aortic balloon pump during high-risk percutaneous coronary intervention in acute coronary syndrome.Materials and methods. Patients required mechanical circulatory support (n=5...

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The objective: to establish the prevalence of postoperative delirium (POD) and the influence of various factors in intra- and postoperative periods on its occurrence in children with septal congenital defects requiring surgical interventions with cardiopulmonary bypass (CPB).Subjects and methods: 40...

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Various pathological factors accompanying any cardiac surgery can cause intraoperative systemic inflammatory responses (SIR). As the number of cardiac surgical interventions grows worldwide, the issue of SIR prevention appears highly relevant.Aim of the study. To determine the effect of not using dono...

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The paper provides an analytical review of the references on the role of microcirculatory disorders in the development of critical conditions, the significance of circulatory monitoring, specifically, to make a presumptive prognosis of multiple organ dysfunction. It defines main directions in the di...

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Lipid peroxidation products and antioxidative system components were studied in 56 patients with a systemic inflammatory response of various genesis. The arterial blood levels of prooxidants were found to be associated with a poor outcome. The findings that there is an inverse correlation between li...

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We studied surface expression of trigger receptor, expressed by myeloid cells-1 (TREM-1) on various subpopulations of monocytes before direct revascularization of myocardium with artificial blood flow and in early postoperative period. We registered that various expression of TREM-1 on the surface c...

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Acute kidney injury (AKI) associated with cardiac surgery in children is one of the most frequent complications of the postoperative period appearing due to various perioperative factors. Generally accepted criteria for the diagnosis of AKI, on the one hand, may underestimate the frequency of develo...

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The immune system in critical illnesses initiates local inflammation in the damaged area. In the absence of a balance between local and systemic inflammations, an infectious or non-infectious systemic inflammatory response follows, which has a stage of "hyper inflammation - compensatory anti-in...

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Patients, due to various reasons not indicated for coronary bypass (CABG), usually have extremely high risk of complications in percutaneous intervention (PCI) as well. Recently it was shown that extracorporeal membrane oxygenation (ECMO) might provide a necessary support in the case of high risk PC...

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Objective: to improve the results of treatment for severe obstetric sepsis by pathogenetically founded continuous renal replacement therapies as extracorporeal homeostatic correction. Subjects and methods. Forty-two women with severe abdominal sepsis were divided into 3 groups: 1) 14 women with seve...

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A differential approach to choosing the methods of extracorporeal detoxification in the complex treatment of abdominal sepsis in the context of endogenous intoxication in order to enhance the efficiency of medical measures was pathogeneti-cally substantiated. In 51 patients diagnosed as having abdom...

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Objective: to analyze the efficiency of renal replacement therapy (RRT) for acute myocardial infarction complicated by cardiogenic shock and multiorgan dysfunction. Subjects and methods. Sixty-six patients with acute myocardial infarction complicated by cardiogenic shock were enrolled in the study....

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Objective: to optimize preoperative preparation of patients with multifocal atherosclerosis and reduced baseline left ventricular ejection fraction for coronary bypass surgery, by providing a rationale for the use of mechanical and medical circulatory support methods. Subjects and methods. Sixty-one...

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Objective: to determine the impact of early initiation of renal replacement therapy on the manifestations of a systemic inflammatory response (SIR) and on the prevention of progression of organ dysfunction (OD). Subjects and methods. A prospective study was conducted in the intensive care units of t...

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Outbreaks of viral infections have become a global healthcare challenge over the last decade. The 2009—2010 flu A (H1N1) outbreak resulted in global pandemia, associated with high morbidity and mortality reaching 31%. Another flu A (H1N1) outbreak occurred in 2015—2016. There is a strong probability...

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Objective: to study the clinical efficiency of introducing an algorithm for organ-protective intensive care. Materials and methods. 3278 case histories of patients admitted to the clinic in 2000—2009 for surgical treatment (under extracorporeal circulation) for coronary heart disease (CHD) and acqui...

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Objective: to analyze the results of treating viral-bacterial pneumonias in pregnant women and puerperas in the 2009 seasonal influenza period. Subjects and methods. Five hundred and seven pregnant women who were admitted to the clinics of three institutions for the diagnosis of pneumonia between Oc...

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The focus of the researchers’ attention today includes the recently discovered role of mitochondria in the immune response. Increasing evidence shows that mitochondrial DNA, in retaining some of their characteristics of the ancient α-proteobacteria’s genome, is a potent immune stimulus for inflammat...

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Background. Orthotopic heart transplantation (OHT) is the gold standard treatment for individuals with endstage heart failure (HF), providing the best survival and quality of life. In Russia, the number of OHT procedures and transplantation of other organs have significantly increased in recent year...

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