Search Results - D. A. Filimonov
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Consequences of the Loss of the Leased Asset for the Parties to the Leasing Agreement by D. A. Filimonov
Published 2015-06-01The article reveals the practical consequences resulting from the loss of the object of lease concerning allocation of the risk of loss between the parties of redemption leasing. The author makes the conclusion that the terms of the leasing subject insurance in the lease agreement should be consider...
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Unjust Enrichment in Leasing Relations by D. A. Filimonov
Published 2014-09-01The practical implications of redemption leasing contract termination are considered in the article. The author comes to the well-founded conclusion that the contract has a complex composition and includes both leasing contract terms and sale and purchase contract terms. The examples of judicial pra...
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Legal Regulation of Compensation for the Damage Caused for Reasons of Urgent Necessity as Considered in the Roman Law and its Reception in the Russian Civil Law by D. A. Filimonov
Published 2013-06-01In the article the attempt is made to take the retrospective view of the Roman law regulation in respect to damage compensation on the whole and the damage caused by justifiable actions in particular. The conclusion is made that the Roman law confessed the damage caused for reasons of urgent necessi...
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ON THE ISSUE OF NATIONAL PECULIARITIES OF MODERNIZATION OF THE RUSSIAN POLITICAL ELITE IN THE XVII CENTURY by D. A. Filimonov
Published 2020-09-01The beginning of the 18th century, the era of the transformations of Peter I, which affected many spheres of the life of Russian society, and, in particular, the restructuring of the upper political elite, were predetermined by the dynamics of the socio-economic and political processes of the XVII c...
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Transformation of the highest political elite in Russia after Peter the Great in the process of “palace coups” by D. A. Filimonov
Published 2022-09-01The article is devoted to the study of the transformation of the highest political elite of the Russian Empire after the death of Peter the Great. This is one of the most difficult and dramatic periods in Russian history, called the era of “palace coups”. The main properties of the Russian political...
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Modernisation of the Russian state’s political elite in the context of peter the great’s transformations by D. A. Filimonov
Published 2021-12-01Early eighteenth century was the age of Peter the Great’s transformations, which affected many spheres of life of Russian society, and, in particular, caused the restructuring of the highest political elite. The reforms were, on the one hand, conditioned by the processes of the late seventeenth cent...
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Improvement of long-term treatment results in oligometastatic colorectal cancer patients by using a combined approach by E. O. Kalmykova, R. V. Ishchenko, O. Yu. Stukalova, D. A. Filimonov
Published 2024-12-01Purpose of the study. To improve the treatment results of patients suffering from CRC with oligometastatic lesion by determining the most effective combination of treatment methods.Patients and methods. The results of treatment of 71 patients with oligometastases of colorectal cancer were analyzed....
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Planning in silico screening and experimental study of the hypoglycemic derivatives of cyclic guanidines by P. M. Vasiliev, A. A. Spasov, K. V. Lenskaya, V. V. Poroikov, D. A. Filimonov, V. A. Anisimova
Published 2014-12-01This article is devoted to the search for new cyclic guanidine derivatives with hypoglycemic activity by means of in silico methods. The results of computer prediction of hypoglycemic effect for nine classes of these compounds were analyzed. Two perspective classes of cyclic guanidine derivatives ha...
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Off-Label Use of Neovasculgen for II–III Degree Foot Frostbite: A Case Report by R. V. Ishchenko, E. Ya. Fistal, D. A. Filimonov, M. V. Pokrovskii, V. V. Arkhipov, S. V. Nalyotov, V. V. Arefiev, V. V. Makienko, E. N. Nalyotova
Published 2024-12-01INTRODUCTION. The high mortality and disability rates associated with cold injury are often a consequence of urgent amputation or disarticulation surgery. The use of the Russian gene therapy product Neovasculgen can decrease the amputation rate in patients with chronic limb ischaemia through prevent...
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In Silico Estimation of the Safety of Pharmacologically Active Substances Using Machine Learning Methods: A Review by V. V. Poroikov, A. V. Dmitriev, D. S. Druzhilovskiy, S. M. Ivanov, A. A. Lagunin, P. V. Pogodin, A. V. Rudik, P. I. Savosina, O. A. Tarasova, D. A. Filimonov
Published 2023-12-01Scientific relevance. Currently, machine learning (ML) methods are widely used in the research and development of new pharmaceuticals. ML methods are particularly important for assessing the safety of pharmacologically active substances early in the research process because such safety assessments s...
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