Search Results - D E Karateev

Достижение стойкой клинической ремиссии при ревматоидном артрите (РА) за последние 10 лет стало реально достижимой задачей для практических ревматологов, в первую очередь в связи с внедрением современных методов терапии генно-инженерными биологическими препаратами (ГИБП) [1]. В случае своевременно у...

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EU Registries Forum Meeting took place 2–3 March 2015 in Chantilly, France. Leading experts in the field participated in the forum. Registersnot only of Western Europe but also of Russia, USA, Canada and Japan were presented at the meeting. The most important directions of development of modern regi...

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Objective. To evaluate basic trends and variability of the course of rheumatoid arthritis, to reveal parameters of long-term prognosis. Material and Methods. 238 pts with RA (30 male, 208 female) were followed for (M±o) I5,5±6,4 years. They were investigated with standard clinical and laboratory met...

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The review considers the specific features of golimumab (GLM), a representative of a group of tumor necrosis factor-α inhibitors primarily by comparing its immunogenicity parameters with other drugs in this group (infliximab, adalimumab, certolizumab pegol, etanercept). Despite its fundamental simil...

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Tumor necrosis factor (TNF) α inhibitors are the most commonly used agents to treat rheumatoid arthritis (RA) and other inflammatory arthropathies. Five drugs belonging to the family of TNFα inhibitors have been certified in Russia for treating RA: infliximab (INF), adali- mumab (ADA), golimumab, ce...

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The current treatment strategy for rheumatoid arthritis (RA) is based on the principles of early aggressive therapy and tight control, which are summarized in «Treat-to-Target» recommendations. The draft RA treatment guidelines by the Association of Rheumatologists of Russia (ARR) reflect these prin...

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The paper considers the very urgent problem of optimization of the management of rheumatoid arthritis (RA) patients who have achieved remission (or persistent low disease activity) during therapy using biologicals. It analyzes the results of BeSt, OPTIMA, HIT HARD, ACT-RAY, AVERT, PRESERVE, RETRO, P...

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Ревматоидный артрит (РА) – широко распространенное (поражено до 1,0% от общей численности населения) воспалительное заболевание суставов. Для РА характерно прогрессирующее течение с формированием деформаций суставов, развитием тяжелых функциональных нарушений и поражений внутренних органов, инвалиди...

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Objective. To perform a comparative assessment of methotrexate and sulfasalazine efficacy when administered as monotherapy and in combination with low doses of GC in early RA considering disease activity and erosions development in joints of hands and feet. Material and methods. 124 pts with RA fulf...

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Review of the USA, Argentina, Australia, Japan, and European Union registries is presented. The similarities and differences between the registries in terms of populations of rheumatoid arthritis patients and the target goals are studied

Some patients with rheumatoid arthritis (RA) are unresponsive or intolerant to both synthetic first-line anti-inflammatory drugs (FLAID) and tumor necrosis factor (TNF) а inhibitors already included into all the treatment standards . Along with the conventional methods for overcoming drug resistance...

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Education programs are an important part of the management of patients with rheumatoid arthritis (RA).Objective: to develop a unified model of an education program for RA patients and to evaluate its efficiency at the early stage of the disease.Material and methods. A group education program was wor...

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The Expert Council for Tofacitinib (TOFA) and two symposiums on New Possibilities for Targeted Therapy of Rheumatoid Arthritis and on Success Factor of Biological Therapy for Rheumatic Diseases were held within the annual scientific-and-practical conference of the V.A. Nasonova Research Institute of...

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Objective: to study the possible chondroprotective effect of the viscoelastic agent synvisc, by applying the developed methodological and classification approaches to evaluating the intraarticular cartilage by arthroscopy and magnetic resonance imaging (MRI).Subjects and methods. Eighty six patients...

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Pain associated with rheumatic diseases of juxta-articular soft tissues (RDJAST) of the pelvis and lower extremity is a frequent reason for seeking advice from general practitioners and rheumatologists. However, the true cause of painful sensations is often overlooked by a physician and the patient...

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