Suchergebnisse - Cong Hu

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  1. 1

    Pharmacokinetics and tissue distribution analysis of ginsenoside Rh3 in rats using a novel LC-MS/MS quantification strategy von Cong Hu, Cong Hu, Yuheng Wang, Yu Liu, Xiaojing Wang, Peifang Song, Hong Ma, Ling Yang, Ling Yang

    Veröffentlicht 2025-07-01

    Introduction:Ginsenoside Rh3 (GRh3), a rare ginsenoside, demonstrates diverse pharmacological activities in vitro; however, the lack of pharmacokinetic and tissue distribution data has limited its translation to in vivo applications. This study aimed to develop and validate a novel liquid chromatogr...

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  2. 2

    Multi-Impairment Compensation for CO-OFDM System Based on Deep Learning and LDPC Code von Cong Hu, Yuanxiang Chen, Ying Han, Jianguo Yu

    Veröffentlicht 2024-01-01

    In this article, we propose a multi-impairment compensation scheme based on deep learning and low-density parity-check (LDPC) code for the coherent optical orthogonal frequency division multiplexing (CO-OFDM) system. We first propose a multi-impairment compensation autoencoder (MICAE) based on deep...

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  3. 3

    Meshless Numerical Simulation on Dry Shrinkage Cracking of Concrete Piles for Offshore Wind Power Turbine von Cong Hu, Jianfeng Xue, Taicheng Li, Haiying Mao, Haotian Chang, Wenbing Zhang

    Veröffentlicht 2025-06-01

    Against the backdrop of the global energy transition, offshore wind power has undergone rapid development. As a vital component of offshore wind power infrastructure, dry shrinkage cracking in concrete piles poses a significant threat to the safe and stable operation of offshore wind power systems....

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  4. 4

    Validation of Biomarkers and Immunotherapy With Crohn’s Disease Using WGCNA and Two-Sample Mendelian Randomization Study von Cong Hu, Shuxiong Nong, Chenang Liu, Yongfeng Chen, Chilin Liao, Meng Wu

    Veröffentlicht 2025-01-01

    Conclusions: The study screened five potential biomarker genes in CD patients using a bioinformatics approach and Mendelian randomization study. Our results provided insights into CXCL1, LCN2, NOS2, S100A8, and DUOX2 in CD and suggested that CXCL1 may potentially be the optimal biomarker that could...

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  5. 5

    Species and Phylogenetic Diversity of Woody Plants Shift With the Elevational Gradient in Subtropical Forests in South China von Jing Li, Yinghua Luo, Feng Chen, Cong Hu, Chaohao Xu, Zhonghua Zhang, Gang Hu

    Veröffentlicht 2025-07-01

    ABSTRACT The distribution of biodiversity along elevational gradients and the drivers of these patterns are research hotspots in community ecology; nonetheless, these aspects remain insufficiently understood. To address this, we established 24 plots along an elevational gradient from 300 to 1400 m o...

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  6. 6

    Dynamic Profiling of Penicillin‐Binding Protein 2a (PBP2a)‐Positive Extracellular Vesicles: Implications for Early Diagnosis and Treatment Monitoring of Methicillin‐Resistant Staph... von Qianqian Gao, Wenwu Zhou, Zhen Shen, Tianchi Chen, Cong Hu, Liang Dong, Da Han, Min Li

    Veröffentlicht 2025-07-01

    ABSTRACT Infections caused by methicillin‐resistant staphylococci (MRS), such as methicillin‐resistant Staphylococcus aureus (MRSA), pose significant challenges to public health. The early detection of MRS infections and monitoring of antibiotic resistance profiles are critical for patient managemen...

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  7. 7

    Activation of MET promotes resistance to sorafenib in hepatocellular carcinoma cells via the AKT/ERK1/2-EGR1 pathway von Qing-Feng Xiang, Mei-Xiao Zhan, Yong Li, Hui Liang, Cong Hu, Yao-Ming Huang, Jing Xiao, Xu He, Yong-Jie Xin, Min-Shan Chen, Li-Gong Lu

    Veröffentlicht 2019-12-01

    Sorafenib is an oral multikinase inhibitor that has become an established therapeutic approach in advanced hepatocellular carcinoma (HCC). However, the benefit of sorafenib in clinical therapy is often affected by drug resistance. Therefore, it is important to explore the mechanisms underlying soraf...

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