Search Results - Chunyan Li
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IGF2BP3 Modulates mRNA Splicing and Stability to Promote Trophoblast Progression via Interaction with PDE3A and Suppression by miR-196a-5p in Preeclampsia
Published 2025-05-01Get full text<b>Background:</b> Preeclampsia (PE) is a pregnancy-specific disorder and a leading cause of maternal and fetal morbidity and mortality. Impaired trophoblast invasion is a hallmark of PE, and alternative splicing (AS) is crucial for trophoblast differentiation and placental development....
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Deaths burden of laryngeal cancer attributable to occupational exposure in the male working age population: findings from global burden of disease study 2021
Published 2025-06-01Get full textObjectivesLaryngeal cancer (LC) is a major health threat to the male working-age population, with occupational exposures (asbestos and sulfuric acid) being key risk factors. However, the deaths burden of LC attributable to occupational exposure in this population remains unclear. This study analyzes...
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Unveiling mitochondrial transfer in tumor immune evasion: mechanisms, challenges, and clinical implications
Published 2025-07-01Get full textBackgroundMitochondrial transfer, the intercellular transmission of mitochondria via tunneling nanotubes(TNTs), extracellular vesicles(Evs), or cell fusion, has emerged as a critical mechanism in cancer progression. Increasing evidence suggests that this phenomenon not only supports tumor cell metab...
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49, XXXYY: Parental Origin, Occurrence, and Clinical Phenotypes
Published 2025-01-01Get full text49, XXXYY is a rare form of sex chromosomal aneuploidy that has been reported in 11 cases worldwide. The parental origin of the extra sex chromosomes and the specific clinical features of this condition remain unclear. We recruited a case with 49, XXXYY and performed genome-wide copy number variatio...
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No difference between CT- and MRI-based patient-specific instrumentation for total knee arthroplasty: an updated systematic review and meta-analysis
Published 2025-07-01Get full textObjectOur previous systematic review of either computed tomography (CT)-based or magnetic resonance imaging (MRI)-based patient-specific instrumentation (PSI) systems in total knee arthroplasty (TKA) included literature up to June 2016. However, the quickly evolving field warranted an update. Theref...
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