Hakutulokset - Chunhui Gu

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    Identification of a stromal immunosuppressive barrier orchestrated by SPP1+/C1QC+ macrophages and CD8+ exhausted T cells driving gastric cancer immunotherapy resistance

    Identification of a stromal immunosuppressive barrier orchestrated by SPP1+/C1QC+ macrophages and CD8+ exhausted T cells driving gastric cancer immunotherapy resistance Tekijä Guichuang Ma, Xiaohan Liu, Qinrui Jiang, Shaowei Li, Qijing Wu, Bishan Liang, Fei Sun, Chunhui Gu, Wangjun Liao, Wangjun Liao, Zhihua Zhang, Min Shi, Qiong Huang

    Julkaistu 2025-07-01

    PurposeThe heterogeneity of immune cells is a critical manifestation of gastric cancer (GC) heterogeneity and significantly contributes to immune therapy resistance. Although previous studies have focused on the roles of specific myeloid cells and exhausted CD8+ T cells in immune resistance, the imm...

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