Search Results - Christophe Pascal

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    Furosemide and Serum Protein-Bound Uremic Toxin Concentrations in Patients With CKD

    Furosemide and Serum Protein-Bound Uremic Toxin Concentrations in Patients With CKD by Margaux Costes-Albrespic, Natalia Alencar de Pinho, Islam Amine Larabi, Carolla El Chamieh, Solène M. Laville, Denis Fouque, Maurice Laville, Luc Frimat, Jean-Claude Alvarez, Ziad A. Massy, Sophie Liabeuf, Natalia Alencar De Pinho, Dorothée Cannet, Christian Combe, Denis Fouque, Luc Frimat, Aghilès Hamroun, Yves-Edouard Herpe, Christian Jacquelinet, Maurice Laville, Sophie Liabeuf, Ziad A. Massy, Pascal Morel, Christophe Pascal, Roberto Pecoits-Filho, Joost Schanstra, Bénédicte Stengel, Céline Lange, Oriane Lambert, Marie Metzger

    Published 2025-07-01

    Introduction: Furosemide is commonly prescribed to patients with chronic kidney disease (CKD) but may impair the kidney’s excretion of protein-bound uremic toxins (PBUTs) via the organic anion transporters 1 and 3 (OAT1 and OAT3). We evaluated the association between furosemide prescription (status...

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    Association of Phenylacetylglutamine and Cognitive Impairment in CKD

    Association of Phenylacetylglutamine and Cognitive Impairment in CKD by Hélène Levassort, Julie Boucquemont, Sophie Liabeuf, Solène M. Laville, Céline Lange, Luc Frimat, Christian Combe, Denis Fouque, Maurice Laville, Christian Jacquelinet, Yves-Edouard Herpe, Islam Amine Larabi, Jean-Claude Alvarez, Natalia Alencar de Pinho, Marion Pépin, Ziad A. Massy, Natalia Alencar de Pinho, Dorothée Cannet, Christian Combe, Denis Fouque, Luc Frimat, Aghilès Hamroun, Yves-Edouard Herpe, Christian Jacquelinet, Maurice Laville, Sophie Liabeuf, Ziad A. Massy, Pascal Morel, Christophe Pascal, Roberto Pecoits-Filho, Joost Schanstra, Bénédicte Stengel, Céline Lange, Oriane Lambert, Marie Metzger

    Published 2025-08-01

    Introduction: Chronic kidney disease (CKD) leads to the accumulation of uremic toxins (UTs). Studies have suggested that UTs are associated with cognitive impairment (CI) in patients with CKD. Recently, studies reported that phenylacetylglutamine (PAG) contributes to the association between CKD and...

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