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    α-Lipoic acid mitigates age-related macular degeneration via ferroptosis: integrative multi-omics and network pharmacology

    α-Lipoic acid mitigates age-related macular degeneration via ferroptosis: integrative multi-omics and network pharmacology by Yaqiong Zhang, Yaqiong Zhang, Yuanyuan Chen, Chenglin Sun, Fang Li, Yin Shen, Yin Shen

    Published 2025-07-01

    BackgroundAge-related macular degeneration (AMD) is a leading cause of irreversible vision loss among the elderly. α-Lipoic acid (ALA), a naturally occurring antioxidant and iron-chelator, has shown potential in modulating ferroptosis, but its mechanism in AMD remains unclear.MethodsNetwork pharmaco...

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