Søgeresultater - Cheng-jun LI
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Development of a cELISA for effective detection of the antibody against H7 subtype of avian influenza virus
Udgivet 2022-01-01Få fuldtekstH7 avian influenza viruses (AIVs) normally circulated among birds before. From 1996 to 2012, human infections with H7 AIVs (H7N2, H7N3, and H7N7) were reported in Canada, Italy, Mexico, the Netherlands, the United Kingdom and the USA. Until March 2013, human infections with H7N9 AIVs were reported i...
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Generation and application of two monoclonal antibodies targeting conserved linear epitopes in the NP protein of influenza A virus
Udgivet 2022-07-01Få fuldtekstMonoclonal antibodies (mAbs) are widely used in virus research and disease diagnosis. The nucleoprotein (NP) of influenza A virus (IAV) plays important roles in multiple stages of the virus life cycle. Therefore, generating conserved mAbs against NP and characterizing their properties will provide u...
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Attenuation of Virulent Porcine Reproductive and Respiratory Syndrome Virus Strain CH-1a and Genetic Variation of ORF5 Gene
Udgivet 2012-12-01Få fuldtekstTo develop a modified live vaccine (MLV) against porcine reproductive and respiratory syndrome virus (PRRSV), virulent CH-1a strain was attenuated by serial passages up to 130 passage (P130) in Marc-145 cells. The virulence and immune efficacy of the attenuated CH-1a were evaluated in pigs. The resu...
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Development of a real-time RT-PCR method for the detection of newly emerged highly pathogenic H7N9 influenza viruses
Udgivet 2017-09-01Få fuldtekstIn 2013, a human influenza outbreak caused by a novel H7N9 virus occurred in China. Recently, the H7N9 virus acquired multiple basic amino acids at its hemagglutinin (HA) cleavage site, leading to the emergence of a highly pathogenic virus. The development of an effective diagnostic method is impera...
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