Search Results - Chao Pi

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  1. 1
    Anti atherosclerosis effect and mechanism of a novel curcumin analogue CACN136: regulating macrophage M1/M2 polarization and lipid metabolism

    Anti atherosclerosis effect and mechanism of a novel curcumin analogue CACN136: regulating macrophage M1/M2 polarization and lipid metabolism by Qianjiao Zhao, Qianjiao Zhao, Qianjiao Zhao, Yueting Zhong, Yueting Zhong, Yueting Zhong, Zheng Li, Zheng Li, Zheng Li, Jia Tang, Jia Tang, Jia Tang, Chao Pi, Chao Pi, Wenwu Zheng, Peng Shi, Ying Zuo, Jun Jiang, Yan Yang, Shifeng Chu, Yumeng Wei, Ling Zhao, Ling Zhao, Ling Zhao

    Published 2025-06-01

    IntroductionCurcumin has been found to inhibit atherosclerosis. However, its poor stability and low activity severely limit its further application. To overcome the shortcomings of curcumin, our team successfully designed a novel curcumin analog, CACN136. This study aims to explore the anti-atherosc...

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  2. 2
    The P2X7 receptor in depression: Novel insights and therapeutic implications

    The P2X7 receptor in depression: Novel insights and therapeutic implications by Yue-ting Zhong, Chao Pi, Ying Zuo, Yan Wei, Wen Li, Yong-qiang Jiang, Lei Tao, Wen-wu Zheng, Jun Jiang, Yan Yang, Shi-feng Chu, Bin-yan Liu, Ke-zhi Liu, Yu-meng Wei, Ling Zhao

    Published 2025-09-01

    Major depressive disorder (MDD) is a heterogeneous mental disorder involving multiple pathogenic mechanisms. Current first-line antidepressant medications suffer from slow onset of action, limited effectiveness, and high side effects, necessitating the search for new therapeutic targets. Targeting c...

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