Search Results - Carol Prives

Carol Prives

Professor Carol L. Prives FRS is the Da Costa Professor of Biological Sciences at Columbia University. She is known for her work in the characterisation of p53, an important tumor suppressor protein frequently mutated in cancer.

Professor Prives is an elected member of the National Academy of Sciences (elected in 2008). Provided by Wikipedia
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    Analysis of p53-Independent Functions of the Mdm2-MdmX Complex Using Data-Independent Acquisition-Based Profiling

    Analysis of p53-Independent Functions of the Mdm2-MdmX Complex Using Data-Independent Acquisition-Based Profiling by Anu Jain, Rafaela Muniz de Queiroz, Jayanta K. Chakrabarty, Karl A. T. Makepeace, Carol Prives, Lewis M. Brown

    Published 2025-05-01

    Background: We utilized data-independent acquisition (DIA) to study the poorly understood biology of Mdm2 and MdmX in a p53-null context. Mdm2 and MdmX form an E3-ligase complex that has as its most well-studied function the negative regulation of the tumor suppressor p53; however, it is also known...

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