Search Results - Can Lin

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    MDDeep-Ace: species-specific acetylation site prediction based on multi-domain adaptation

    MDDeep-Ace: species-specific acetylation site prediction based on multi-domain adaptation by Yu Liu, Chaofan Ye, Can Lin, Kangkang Mao, Ming Zhu

    Published 2025-07-01

    Background Lysine post-translational modification (PTM) is pivotal in regulating diverse cellular processes, profoundly impacting protein structure and function. Over recent decades, numerous experimental techniques have advanced PTM site identification, significantly contributing to research progre...

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    Engineered red blood cell extracellular vesicles for delivery of Dox and siIDO1 enhance targeted chemo-immunotherapy of acute myeloid leukemia

    Engineered red blood cell extracellular vesicles for delivery of Dox and siIDO1 enhance targeted chemo-immunotherapy of acute myeloid leukemia by Jing Yang, Ling Zhang, Nan Wu, Jiayuan Hu, Jun Ren, Xinyi Chen, Xingyu Wei, Minghui Sun, Ziwei Li, Yongcan Liu, Yan Shu, Genyou Li, Fangfang Jin, Can Lin, Lisha Tang, Zesong Yang

    Published 2025-07-01

    Background As a malignancy of hematopoietic origin, the standard-of-care cytoreductive chemotherapy can not provide satisfactory treatment effect for patients with acute myeloid leukemia (AML). Immunotherapy has received increasing attention in leukemia treatment. However, the immunosuppressive micr...

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