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    SITA: Predicting site-specific immunogenicity for therapeutic antibodies

    SITA: Predicting site-specific immunogenicity for therapeutic antibodies av Yewei Cun, Hao Ding, Tiantian Mao, Yuan Wang, Caicui Wang, Jiajun Li, Zihao Li, Mengdie Hu, Zhiwei Cao, Tianyi Qiu

    Publicerad 2025-06-01

    Antibody humanization is critical to reduce immunogenicity and enhance efficacy in the preclinical phase of the development of therapeutic antibodies originated from animal models. Computational suggestions have long been desired, but available tools focused on immunogenicity calculation of whole an...

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