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    Canadian Adaptive Platform Trial of Treatments for COVID in Community Settings (CanTreatCOVID): protocol for a randomised controlled adaptive platform trial of treatments for acute SARS-CoV-2 infection in community settings

    Canadian Adaptive Platform Trial of Treatments for COVID in Community Settings (CanTreatCOVID): protocol for a randomised controlled adaptive platform trial of treatments for acute... par Catherine Hudon, Kris Aubrey-Bassler, Vivian R Ramsden, Machelle Wilchesky, Paul Little, Michelle Greiver, Rahim Moineddin, Ryan Zarychanski, Jean-Eric Tarride, Annie Leblanc, Peter Jüni, Dee Mangin, Robert Fowler, Srinivas Murthy, Jennifer Rayner, Alexander Singer, Yoav Keynan, Simone Dahrouge, Emily Gard Marshall, Rita McCracken, Sabrina T Wong, David J A Jenkins, Kerry McBrien, Nav Persaud, Anita Srivastava, Jennifer Isenor, Todd C Lee, Christopher C Butler, John C Marshall, Stephanie Garies, Valeria E Rac, Ross E G Upshur, Peter Selby, Marie-Thérèse Lussier, Sarvesh Logsetty, Andrew David Pinto, Melissa Andrew, Brianne Wood, Emily G McDonald, Amanda Condon, Aisha Lofters, Christine Leong, Lynora Saxinger, Rachel Walsh, Abhimanyu Sud, Sylvain Lother, Jean-Sébastien Paquette, David Barber, Brendan Barrett, Rae Spiwak, Sakina Walji, Ali Damji, Banafshe Hosseini, Bruno R. da Costa, Peter Daley, Noah Crampton, Jennifer Hulme, Rosemarie Lall, Laura Maclaren, Brianna Orava, Jay Jae Hee Park, Diana C. Sanchez-Ramirez, Haolun Shi, Deanna Telner, Barb Zelek, Jolanta Piszczek, Daniel Warshafsky

    Publié 2025-08-01

    Introduction SARS-CoV-2 is now endemic and expected to remain a health threat, with new variants continuing to emerge and the potential for vaccines to become less effective. While effective vaccines and natural immunity have significantly reduced hospitalisations and the need for critical care, out...

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