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    Gene-regulatory programs that specify age-related differences during thymocyte development

    Gene-regulatory programs that specify age-related differences during thymocyte development av Divya Ganapathi Sankaran, Hongya Zhu, Viviana I. Maymi, Isabel M. Forlastro, Ya Jiang, Nathan Laniewski, Kristin M. Scheible, Brian D. Rudd, Andrew Grimson

    Publicerad 2025-07-01

    Summary: T cell development is fundamental to immune system establishment, but how this development changes with age remains poorly understood. Here, we construct a transcriptional and chromatin accessibility atlas of T cell developmental programs in neonatal and adult mice, revealing the ontogeny o...

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