Risultati della ricerca - Beau Ances
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Psychosocial behavioral phenotypes of racially/ethnically minoritized older adults enrolled in HABS‐HD differ on neuroimaging measures of brain age gap, hippocampal volume, and cor... di Alexandra L. Clark, Makenna B. McGill, Alexandra J. Weigand, Julie K. Wisch, Kalen Petersen, Beau Ances, Meredith N. Braskie, Sid O'Bryant, Kelsey R. Thomas, HABS‐HD Study Team
Pubblicazione 2025-04-01Abstract INTRODUCTION This study examined whether previously identified psychosocial behavioral phenotypes differed on structural neuroimaging markers. METHODS Latent profile analysis (LPA) employed in a sample of 1820 community‐dwelling older adults (1118 Hispanic and 702 Black) replicated previous...
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Mediating role of Interleukin-6 in the predictive association of diabetes with Hippocampus atrophy, Amyloid, Tau, and Neurofilament pathology at pre-clinical stages of diabetes-rel... di Asma Hallab, Sid E. O'Bryant, Kristine Yaffe, Arthur Toga, Robert Rissman, Leigh Johnson, Meredith Braskie, Kevin King, James R. Hall, Melissa Petersen, Raymond Palmer, Robert Barber, Yonggang Shi, Fan Zhang, Rajesh Nandy, Roderick McColl, David Mason, Bradley Christian, Nicole Phillips, Stephanie Large, Joe Lee, Badri Vardarajan, Monica Rivera Mindt, Amrita Cheema, Lisa Barnes, Mark Mapstone, Annie Cohen, Amy Kind, Ozioma Okonkwo, Raul Vintimilla, Zhengyang Zhou, Michael Donohue, Rema Raman, Matthew Borzage, Michelle Mielke, Beau Ances, Ganesh Babulal, Jorge Llibre-Guerra, Carl Hill, Rocky Vig
Pubblicazione 2025-08-01Introduction: Type-2 diabetes (T2DM) has been associated with higher dementia risks, but the mechanisms are still unclear, and there is increasing evidence of the role of cytokines. Interleukin-6 (IL-6) mediating effect has never been explored. Methods: The study included a subset of 1927 community-...
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