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    De novo assembly of RNA m6A modification factors into viral genome-associated nuclear bodies drives HCMV RNA accumulation

    De novo assembly of RNA m6A modification factors into viral genome-associated nuclear bodies drives HCMV RNA accumulation por Rebecca C. Grande, Chia-Ching Lin, Michael Cammer, Ebube D. Emesom, Maaz Asher Khurram, Chris Boutell, Lance T. Denes, Timothée Lionnet, Angus C. Wilson, Ian Mohr

    Publicado 2025-07-01

    Summary: The factors that install and recognize N6-methyladenosine (m6A) on RNA to regulate gene expression are well characterized, but how their spatial organization responds to physiological stress, including infection, is unclear. Here, we show that human cytomegalovirus (HCMV) infection induces...

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