Search Results - Angelo Schenone

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  1. 1
    A Comprehensive Description of the Roadmap to Identify and Validate a Myelin Biomarker

    A Comprehensive Description of the Roadmap to Identify and Validate a Myelin Biomarker by Giovanna Capodivento, Davide Visigalli, Andrea Armirotti, Chiara Demichelis, Marinella Carpo, Roberto Fancellu, Erika Schirinzi, Daniele Severi, Diego Franciotta, Fiore Manganelli, Gabriele Siciliano, Alessandro Beronio, Elisabetta Capello, Paola Lanteri, Eduardo Nobile-Orazio, Angelo Schenone, Luana Benedetti, Lucilla Nobbio

    Published 2025-06-01

    Background: Demyelination and remyelination are major issues for scientists dealing with myelin disorders in both clinical and research fields. Despite that, rapid, reliable and convenient tools to monitor myelin changes still lack both in central and peripheral nervous system. Given that myelin is...

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  2. 2
    Increased [<sup>18</sup>F]DPA-714 Uptake in the Skeletal Muscle of SOD1<sup>G93A</sup> Mice: A New Potential of Translocator Protein 18 kDa Imaging in Amyotrophic Lateral Sclerosis

    Increased [<sup>18</sup>F]DPA-714 Uptake in the Skeletal Muscle of SOD1<sup>G93A</sup> Mice: A New Potential of Translocator Protein 18 kDa Imaging in Amyotrophic Lateral Sclerosis by Cecilia Marini, Mattia Riondato, Edoardo Dighero, Alessia Democrito, Serena Losacco, Laura Emionite, Lucilla Nobbio, Irene Di Patrizi, Mattia Camera, Chiara Ghersi, Maddalena Ghelardoni, Francesco Lanfranchi, Francesca Vitale, Sonia Carta, Sabrina Chiesa, Carola Torazza, Marco Milanese, Matteo Bauckneht, Mehrnaz Hamedani, Federico Zaottini, Angelo Schenone, Carlo Martinoli, Federica Grillo, Gianmario Sambuceti

    Published 2025-05-01

    Purpose: The skeletal muscle has been proposed to contribute to the progressive loss of motor neurons typical of amyotrophic lateral sclerosis (ALS). However, this mechanism has not yet been clarified due to the lack of suitable imaging tools. Here, we aimed to verify whether PET imaging of the tran...

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