Search Results - Amol Tatode

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    Engineered Exosomes as Smart Drug Carriers: Overcoming Biological Barriers in CNS and Cancer Therapy

    Engineered Exosomes as Smart Drug Carriers: Overcoming Biological Barriers in CNS and Cancer Therapy by Tanvi Premchandani, Amol Tatode, Jayshree Taksande, Milind Umekar, Mohammad Qutub, Ujban Md Hussain, Priyanka Singanwad

    Published 2025-04-01

    Engineered exosomes have emerged as transformative drug carriers, uniquely equipped to overcome biological barriers in central nervous system (CNS) disorders and cancer therapy. These natural extracellular vesicles, derived from cell membranes, offer inherent biocompatibility, low immunogenicity, an...

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    Deciphering the Structural and Functional Paradigms of <i>Clostridioides difficile</i> Toxins TcdA and TcdB

    Deciphering the Structural and Functional Paradigms of <i>Clostridioides difficile</i> Toxins TcdA and TcdB by Mohammad Qutub, Amol Tatode, Ujban Md Hussain, Tanvi Premchandani, Jayshree Taksande, Milind Umekar, Deepak Thakre

    Published 2025-04-01

    <i>Clostridioides difficile</i> Infection (CDI) continues to be a major cause of antibiotic-associated diarrhea and pseudomembranous colitis, fueled in large measure by virulence factors TcdA and TcdB. These giant glucosyltransferase toxins interfere with host cytoskeletal integrity and...

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