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    Cytokine signaling defects in primary atopic diseases—an updated review

    Cytokine signaling defects in primary atopic diseases—an updated review par Vaishali Thakur, Rakesh Kumar Pilania, Arunima Sharma, Saniya Sharma, Alfred Thomas Mario, Taru Goyal, Madhubala Sharma, Gayathri Coimbatore Vaitheeswaran, Pandiarajan Vignesh, Surjit Singh, Manpreet Dhaliwal, Amit Rawat

    Publié 2025-07-01

    Primary atopic disorders (PADs) are monogenic conditions associated with severe, early-onset atopic diseases. Clinically, they often overlap with polygenic allergic conditions, making specialized laboratory testing necessary to distinguish them from polygenic atopy. Multisystem involvement, such as...

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