Suchergebnisse - Alexandra Calmy

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  1. 1
    Persistent difficulties in switching to second-line ART in sub-saharan Africa--a systematic review and meta-analysis.

    Persistent difficulties in switching to second-line ART in sub-saharan Africa--a systematic review and meta-analysis. von Yoann Madec, Sandrine Leroy, Marie-Anne Rey-Cuille, Florence Huber, Alexandra Calmy

    Veröffentlicht 2013-01-01

    <h4>Objectives</h4>Switching to second-line antiretroviral therapy (ART) largely depends on careful clinical assessment and access to biological measurements. We performed a systematic review and meta-analysis to estimate the incidence of switching to second-line ART in sub-Saharan Afric...

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  2. 2
    Low sensitivity of the fourth‐generation antigen/antibody HIV rapid diagnostic test Determine™ HIV Early Detect for detection of acute HIV infection at the point of care in rural Eswatini: a diagnostic accuracy study

    Low sensitivity of the fourth‐generation antigen/antibody HIV rapid diagnostic test Determine™ HIV Early Detect for detection of acute HIV infection at the point of care in rural E... von Iza Ciglenecki, Nombuso Ntshalintshali, Esther Mukooza, Skinner Lekelem, Mpumelelo Mavimbela, Sindisiwe Dlamini, Lenhle Dube, Nomvuyo Mabuza, Melat Haile, Tom Ellman, Antonio Flores, Olivia Keiser, Sindy Matse, Roberto de laTour, Alexandra Calmy, Bernhard Kerschberger

    Veröffentlicht 2025-07-01

    Abstract Introduction The diagnosis of acute HIV infection (AHI) is challenging in routine settings because it cannot be detected by routine third‐generation antibody rapid diagnostic tests (RDTs). The current fourth‐generation antibody/antigen RDT, Determine™ HIV Early Detect, has demonstrated high...

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