Search Results - A. V. Govorin

Aim: to study selenium, glutathione, glutathione-peroxidase and glutathione-reductase levels in blood in patients with anemia cardiomyopathy previously and after the treatment of Sorbifer and Neoselenium. Selenium levels were investigated by mass concentration method in 48 patients with anemia cardi...

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At present experimental and clinical data confirming efficacy of magnesium-containing drugs in different cardiovascular diseases are obtained. Physiological significance of magnesium is determined by its intracellular fraction. That is why it is desirable to use magnesium with the components contrib...

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Objective: to study the time course of changes in the cytokine profile, the parameters of lipid peroxidation (LPO), antioxidant defense, and lipid spectrum during Arthra therapy in patients with primary osteoarthritis (POA). Subjects and methods. The study was conducted in 26 POA patients (aged 39.5...

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The results of large-scale clinical trials have convincingly demonstrated the effectiveness of acetylsalicylic acid (ASA) in primary and secondary prevention of atherothrombotic events. Studies on the safety of different ASA formulations have been continuing. Magnesium hydroxide included in combined...

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Aim. To study the structural and functional parameters of the heart, as well as the effect of antiviral therapy on certain cardiohemodynamic parameters in patients with viral liver cirrhosis (VLC).Material and methods. 96 patients with VLC (median age 42.1 [36;44] years, median duration of the disea...

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Aim. To study the endothelium status and determine the correlation between endothelial dysfunction and glucose metabolism in men with gout associated with arterial hypertension (HT).Material and methods. Patients (n=175, all are males) with gout were enrolled into the study. Ambulatory blood pressur...

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Aim. To study the changes of the left (LV) and right (RV) ventricles diastolic function, the segmental LV diastolic function in patients with anemic cardiomyopathy after the iron and selenium drugs therapy.Material and methods. Patients (n=54) with severe chronic post-hemorrhagic iron deficiency ane...

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Aim. To study blood levels of non-esterified fatty acids (NEFAs) and adenyl nucleotides, and fatty acids levels in lipids of erythrocyte membranes in patients with primary gout associated with arterial hypertension (HT). Material and methods. 175 male patients with primary gout were included in the...

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The aim. of work was to study the relationship between structural and functional changes in the myocardium and the parameters of heart rate variability in patients with chronic prostatitis. The study included 51 patient with chronic prostatitis of average age 34,2 ± 8,1 years. The study excluded pat...

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For today there are convincing evidences of beneficial effect of ω-3 polyunsaturated fatty acids (PUFA) - eicosapentaenoic (EPA) and docosahexaenoic (DHA) acids – in a number of cardiovascular diseases. Efficacy of ω-3 PUFA was confirmed by results of the large-scale clinical trials. Data on ω-3 PUF...

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Aim. To investigate cardiohemodynamic parameters and serum cytokine levels in patients with severe alcohol intoxication (AI). Material and methods. In total, 100 patients with severe AI were examined. All participants underwent 24-hour electrocardiogram (ECG) monitoring, echocardiography (EchoCG), a...

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Inflammatory markers and activity of lymphocyte-to-platelet adherence (LTA) have been studied in fifty-eight patients with osteoarthritis. Sixteen healthy individuals were included in the control group. Changed production of inflammatory cytokines, i.e. an increased concentration of pro-inflammatory...

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To study the peculiarities of hemodynamics of liver and heart Doppler echocardiography, duplex ultrasonography vascular screening in patients with viral cirrhosis were held. It was found that patients with viral cirrhosis have remodeling of viscerogenic hemodynamic, left ventricle myocardium with fo...

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Material and methods. 55 patients with VLC class А, B, C according to Сhild-Pugh were examined. The average age of patients 42 years, disease duration – 3,8 years. Depending on the presence of ascites, patients were divided into 2 groups: 28 patients had no ascites (group 1), 27 patients had ascites...

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Aim. To investigate on the prevalence, and opportunities for prediction of pulmonary hypertension in patients with liver cirrhosis of viral origin (VLC).Material and methods. The results analyzed, of the investigation of 85 VLC patients. Mean age 40,1 y. o. According to the severity of pulmonary hyp...

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Aim. To study the effect of antiviral therapy on some hemodynamic parameters of the heart and the liver in patients with viral cirrhosis.Material and methods. In 75 patients with chronic viral cirrhosis evaluation of segmental systolic and diastolic function using pulsed tissue Doppler mapping and g...

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Abstract. Blood serum levels of cytokines (Il-1β, TNFα, IL-2, IL-4, IL-6, IL-8, IL-10, IL-20, IL-23),  cytokine soluble receptors (SRp55 TNFα, SR IL-6), as well as markers of insulin resistance were studied in  a group of male patients with primary gout. Increased levels of the above cytokines and d...

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Aim. To study some structural and functional indicators of the right heart, as well as the effect of antiviral therapy on these parameters in patients with viral liver cirrhosis (VLC).Material and methods. Patients with VLC (n=98; mean age 40.6 years, disease duration 3.9 years) were examined. The p...

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Aim. To study some structural and functional parameters of the heart and the parameters of hepato-lienal blood flow in patients with chronic viral hepatitis (CVH).Material and methods. 74 patients with CVH were examined, the average age was 41 years, the disease duration – 3.6 years. The patients we...

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Aim. Studies on the role of autonomic disorders, changes of serum NEFA, glycerol, adenine nucleotides and violation fraction of the fatty acids of erythrocyte membranes in the development of cardiac arrhythmias in patients with chronic prostatitis. Methods. The study included 50 patients with chroni...

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