Search Results - A. M. Semenov

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  1. 1
    Non-immunogenic staphylokinase in patients with massive intermediate-high risk pulmonary embolism: protocol of the FORPE-2 multicenter, double-blind, randomized, placebo-controlled trial

    Non-immunogenic staphylokinase in patients with massive intermediate-high risk pulmonary embolism: protocol of the FORPE-2 multicenter, double-blind, randomized, placebo-controlled... by S. N. Tereshchenko, E. B. Yarovaya, S. G. Leontiev, I. S. Yavelov, R. M. Shakhnovich, A. D. Erlikh, T. M. Uskach, D. V. Duplyakov, V. A. Kutsenko, O. E. Ivlev, A. G. Soplenkova, A. M. Semenov, M. P. Semenov, S. V. Ivanov, S. S. Markin

    Published 2025-03-01

    Aim. To evaluate the efficacy and safety of single bolus administration of non-immunogenic staphylokinase in comparison with placebo in patients with intermediatehigh risk pulmonary embolism (PE) within the FORPE-2 clinical trial.Material and methods. Non-immunogenic staphylokinase has high thrombol...

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  2. 2
    Advanced results of Fortelyzin® use in the FRIDOM1 study and real clinical practice

    Advanced results of Fortelyzin® use in the FRIDOM1 study and real clinical practice by V. A. Markov, D. V. Duplyakov, S. L. Konstantinov, G. V. Klein, S. B. Aksentiev, D. Yu. Platonov, E. V. Vyshlov, Е. A. Ponomarev, R. M. Rabinovich, E. L. Makarov, E. V. Kulibaba, D. S. Yunevich, O. V. Kritskaya, E. A. Baranov, O. B. Talibov, V. A. Kutsenko, A. A. Orlovsky, N. L. Vyazova, A. G. Koledinsky, A. M. Semenov, M. P. Semenov, E. B. Yarovaya, T. M. Uskach, R. M. Shakhnovich, S. N. Tereshchenko, S. S. Markin

    Published 2022-09-01

    Aim. To study the effectiveness of Fortelyzin® in subgroups with different body weights in patients with ST-segment elevation acute myocardial infarction (STEMI) in the FRIDOM1 study and real clinical practice.Material and methods. Fortelyzin® was administered in a single-bolus dose of 15 mg over 10...

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  3. 3
    Non-immunogenic staphylokinase — a thrombolytic agent in the treatment of massive pulmonary embolism: results of the FORPE clinical trial

    Non-immunogenic staphylokinase — a thrombolytic agent in the treatment of massive pulmonary embolism: results of the FORPE clinical trial by A. I. Kirienko, S. G. Leontyev, E. B. Yarovaya, S. I. Konstantinov, B. B. Orlov, Imad Meray, D. V. Duplyakov, V. E. Oleynikov, E. Yu. Vasilyeva, E. A. Ponomarev, S. A. Pribylov, A. G. Komarova, V. V. Bobkov, R. M. Rabinovich, G. V. Klein, Z. S. Shogenov, Yu. V. Karabach, V. N. Zolkin, V. V. Kulabukhov, V. V. Kashtalap, K. A. Linev, G. I. Stryabkova, N. V. Yasnopolskaya, V. Yu. Tolmacheva, Zh. Yu. Chefranova, Yu. A. Lykov, E. S. Panina, N. V. Solovieva, E. V. Rybin, N. V. Furman, E. V. Kulibaba, V. V. Makukhin, A. G. Koledinsky, I. S. Mullova, N. A. Cherepanova, T. V. Pavlova, P. P. Savvinova, I. A. Libov, A. S. Igoshin, I. Yu. Bogomazov, T. B. Pecherina, L. O. Lyudnev, P. N. Vlasov, I. V. Avdeeva, D. B. Maksimov, E. V. Komissarova, V. S. Ivanov, N. L. Vyazova, E. V. Vyshlov, D. S. Kurtasov, V. A. Kutsenko, O. E. Ivlev, A. G. Soplenkova, S. N. Tereshchenko, I. S. Yavelov, R. M. Shakhnovich, A. D. Erlikh, O. B. Talibov, A. M. Semenov, M. P. Semenov, S. V. Ivanov, Yu. A. Romashova, V. V. Beregovykh, A. I. Archakov, S. S. Markin

    Published 2024-12-01

    Aim. To assess the safety and efficacy of a single intravenous bolus of non-immunogenic staphylokinase compared with alteplase in patients with massive pulmonary embolism and hemodynamic instability. Non-immunogenic staphylokinase is a modified recombinant staphylokinase with low immunogenicity, hig...

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