Search Results - A. E. Karateev

Modern therapy for rheumatoid arthritis (RA) allows not only to reduce the activity of immune-mediated inflammation and slow down the progression of the disease, but also to quickly eliminate the main symptoms that cause the most concern to patients, such as pain, functional disorders, fatigue. This...

Full description

The glycosaminoglycan-peptide complex (GPC) Rumalon is a popular injectable drug used to treat osteoarthritis (OA). GPC was one of the world’s first drugs designed for the pharmacotherapy of this disease. The drug has been rigorously tested for efficacy and safety in a series of international placeb...

Full description

Nonsteroidal anti-inflammatory drugs (NSAIDs) are the most popular medications to relieve the symptoms of rheumatoid arthritis (RA). However, NSAIDs can cause serious gastrointestinal, cardiovascular, and renal complications. To take into account risk factors and to use safer NSAIDs and gastroprotec...

Full description

Objective. To study efficacy and tolerability of Normase® (lactulose, Doctor Reddy’s laboratories) for correction of stool disturbances in pts with rheumatic diseases (RD). Material and methods. 50 pts with RD (female with mean age 64,2+19,6 years) suffering from constipation (stool frequency less t...

Full description

.

Analgesic therapy is an essential element of combination treatment in patients with rheumatic diseases (RDs). However, pain killers can cause serious complications. This risk is especially great in patients with comorbidities. Therefore, the individual choice of pharmacological agents for controllin...

Full description

Nonsteroidal anti-inflammatory drugs (NSAIDs) are the mainstay of pathogenetic therapy for acute and chronic pain associated with rheumatic diseases. It would seem that NSAIDs are well studied: their pharmacological properties are known; the fields of their applications, the efficacy of the drugs in...

Full description

Control of chronic pain is one of the main elements of the complex therapy of rheumatic diseases (RD). The use of analgesics is of fundamental importance for the management of patients with osteoarthritis (OA), since a unified system of pathogenetic therapy has not yet been developed for this diseas...

Full description

Controlling acute and chronic musculoskeletal pain (MSP) is a priority in the management of patients with musculoskeletal disorders. This includes widespread conditions such as non-specific back pain (NSBP), osteoarthritis (OA), and periarticular soft tissue disorders, affecting over 1 billion peopl...

Full description

Effective pain control is the most important clinical task in the treatment of osteoarthritis (OA). The International Expert Council, which discussed the possibility of introducing the principle of "treatment to target" to OA treatment, recognized the PASS (patient acceptable symptoms stat...

Full description

Etoricoxib is one of the most popular representatives of a group of nonsteroidal anti-inflammatory drugs (NSAIDs), which is widely used in Russia and other countries of the world. It is a highly selective cyclooxygenase 2 inhibitor that has a rapid and pronounced analgesic effect, a high antiinflamm...

Full description

Nonsteroidal anti-inflammatory drugs (NSAIDs) are a main tool used in real clinical practice to relieve acute pain and to control major symptoms in chronic diseases of the joint and spinal column. They are effective and easy-to-use; however, they may cause adverse reactions (ARs) that require carefu...

Full description

Nonspecific low back pain (NLBP) is one of the most common rheumatic disorders; it is responsible for the greatest number of patients seeking medical advice. Unfortunately, there is neither a generally acknowledged viewpoint on the nature of this pathology nor a unified conception of its treatment i...

Full description

Etodolac is a nonsteroidal anti-inflammatory drug (NSAID), a moderately selective cyclooxygenase-2 inhibitor, which has been already used in clinical practice for more than 30 years as a universal analgesic and anti-inflammatory agent. Etodolac has proven itself in relieving acute pain associated wi...

Full description

Nonsteroidal anti-inflammatory drugs (NSAIDs) are the most popular tool to combat pain. Unfortunately, NSAIDs can cause various adverse reactions, among these one of the most common ones is the development or destabilization of hypertension. Controlled and observational studies have shown that the u...

Full description

Hyaluronic acid (HA) is an effective and safe medication for local injection therapy (LIT) widely used in the treatment of osteoarthritis (OA) of large joints. The therapeutic effect of HA is determined both by the replacement of the lubricating function of natural hyaluronate (viscosupplementation)...

Full description

Throughout the history of rheumatology, the attitude to pain has changed significantly. In the XIX and early XX centuries, pain was considered only as one of the symptoms, the control of which is secondary to the etiotropic and pathogenetic therapy of rheumatic diseases (RD). However, already in the...

Full description

Chronic pain is the main manifestation of rheumatic diseases (RD), it determines the main complaints and worsens the quality of life of patients. The problem of effective control of chronic pain in rheumatology remains a current issue despite the successes in the development of new drugs for pathoge...

Full description

Periarticular soft tissue disorders (PSTD) are typical manifestation of immunoinflammatory rheumatic diseases, primarily spondyloarthritis. However, in real clinical practice, physicians involved in the management of patients with musculoskeletal diseases often have to deal with "non-systemic&q...

Full description

The paper presents the results of a survey of 846 Russian physicians (neurologists, rheumatologists, orthopedic traumatologists, general practitioners, and therapists), whose work is associated with the treatment of musculoskeletal pain. The physicians have been asked to answer which topics they con...

Full description