Résultats de la recherche - A. A. Lebedeva
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The role of education in the dialogue of civilizations
Publié 2009-04-01Accéder au texte intégralТезис о том, что образование способствует диалогу между народами, кажется очевидным. Но почему это происходит? Есть ли какие-либо ограничения для данного утверждения? Каковы механизмы, обеспечивающие диалог цивилизаций? Что вообще происходит с образованием в современном мире? Каковы тенденции его ра...
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Prospects for the development of digital forms of political participation of generation Z in modern Russia
Publié 2021-01-01Accéder au texte intégralThe article considers the forms of political participation of generation Z in modern Russia and gives an assessment of the prospects for digital forms of this participation. The paper describes the characteristics that distinguish generation Z in terms of the influence of these characteristics on th...
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Screening for anxiety and depression in the general population: Adaptation of the Patient Health Questionnaire-4 in Russia
Publié 2024-06-01Accéder au texte intégralThe Patient Health Questionnaire-4 (PHQ-4) is one of the most well-known and widely used instruments for assessing anxiety and depressive symptoms.Objective. The aim of this study was to adapt the Russian-language version of the PHQ-4 in the general population.Material and Methods. Data collection w...
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Glioblastoma: a molecular genetic portrait and modern therapeutic strategies for drug treatment
Publié 2021-11-01Accéder au texte intégralGlioblastoma multiforme is the most common and malignant primary tumor of the central nervous system. Despite the existing modern complex therapy and advances in the study of molecular genetic changes in this tumor, the prognosis for patients with glioblastoma is one of the most unfavorable in oncol...
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Endothelial dysfunction and thrombotic events in patients with severe novel coronavirus infection COVID-19
Publié 2022-05-01Accéder au texte intégralIntroduction. The novel coronavirus infection COVID-19 (NCI COVID-19) caused by the COVID-19 virus, which occurs in the most severe forms, is accompanied not only by the development of respiratory failure and acute respiratory distress syndrome, but also by other equally dangerous complications such...
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Eosinophilic granulomatosis with polyangiitis in comorbidpatient: is the immunological diagnostics always unambiguous
Publié 2020-04-01Accéder au texte intégralEosinophilic granulomatosis with polyangiitis (EGPA), previously called Churg—Strauss syndrome, represents a rare form of ANCA-associated necrotising vasculitis which affects small vessels. This disease is characterized by typical combination of immunological disturbances, hypereosinophilia, severe...
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Plasma cytokines in patients with COVID-19 during acute phase of the disease and following complete recovery
Publié 2021-05-01Accéder au texte intégralCOVID-19, an infection caused by the new coronavirus SARS-CoV-2, is associated with a number of pathophysiological mechanisms, mobilizing a wide spectrum of biomolecules, mainly, cytokines.The purpose of this study was to evaluate levels of multiple cytokines in blood plasma from the patients with C...
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Validation of high-throughput sequencing-based test system for detection of microsatellite instability in colorectal cancer samples
Publié 2025-04-01Accéder au texte intégralIntroduction. Currently in routine clinical practice, standard methods based on polymerase chain reaction (PCR) and immunohistochemical examination are used to determine microsatellite instability (MSI) and deficient mismatch repair system (dMMR). MSI identification using high-throughput sequencing...
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