Search Results - S. A. Boytsov

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ASCOT study results influenced the content of the British National guidelines on arterial hypertension (AH) 2006 and the European Hypertension Society guidelines 2007. This study demonstrated that AH treatment with “new” antihypertensives (calcium antagonists, ACE inhibitors) is more effective and m...

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Background. In the Russian Federation (RF), the prevalence of cardiovascular disease (CVD) and CVD mortality levels are very high. Selected aspects of cardiovascular risk factor (RF) control and preventive activity of healthcare professionals have been investigated in numerous studies; however, rela...

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A multi-tenant database cluster is a concept of a data-storage subsystem for cloud applications with the multi-tenant architecture. The cluster is a set of relational database servers with the single entry point, combined into one unit with a cluster controller. This system is aimed to be used by ap...

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One of the main trends of recent years in software design is a shift to a Software as a Service (SaaS) paradigm which brings a number of advantages for both software developers and end users. However, along with these benefits this transition brings new architectural challenges. One of such challeng...

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Aim. To assess the percentage of the patients who receive lipid-lowering drug therapy and achieve target levels of low-density lipoprotein cholesterol (LDL–CH), in accordance with the recommendations by the Russian Cardiology Society (RCS) and the 4th Joint European Task Force (4JETF).Material and m...

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Healthy nutrition decreases the risk of cardiovascular disorders (CVD). Optimal content of fatty acids is an important point in clinical guidelines. However, during more than a half century of observation, the influence of fatty acids on CVD development is still debated. Recent decades, there has be...

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Endothelium glycocalyx (EG) is a highly organized protecting complex of the vessels. Damage of EG is one of the first pathogenetic mechanisms of a range of pathologies onset, and primarily cardiovascular diseases. Current paper focuses on the structure, functioning of EG normally and in pathology, a...

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Angiotensin II receptor antagonists (ARA) established their position recently duet to new indications above arterial hypertension (HT). These are chronic heart failure, history of myocardial infarction, atrial fibrillation and metabolic syndrome. Analysis of evidence basis, including recently publis...

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Due to low effectiveness of arterial hypertension (AH) monotherapy, recent debates have concentrated on evidence-based effectiveness and safety of combined AH therapy. To improve treatment compliance, reduce treatment costs, and increase therapy effectiveness, fixed-dose combined antihypertensive th...

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The increase in cardiovascular morbidity and mortality in the second half of the 20th century was mainly determined by the lifestyle and lifestyle-associated risk factors (RF). Russian epidemiologic and preventive studies, performed by the USSR Research Cardiology Centre (USSR Academy of Medical Sci...

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The article is focused on the reasons for lack of a precise data and issues related to population assessment of morbidity/mortality in subsequent myocardial infarctions (re-MI). Significant factors for re-MI development are age older than 60 y., comorbidities, treatments. The evaluation and signific...

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In modern Russia, the initiative budgeting mechanism has been developing systematically since 2015. The practice has been launched in 51 out of 85 constituent entities of the Russian Federation. This phenomenon is an urgent topic for research, in connection with its priority for the state as one of...

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The article discusses the statement of the diagnosis of hypertension (HTN) with severe left ventricular systolic dysfunction and the resulting decrease in systolic blood pressure (BP) to target levels or hypotension ("decapitated hypertension").The current Russian guidelines on HTN in adul...

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At the present time ischemic heart disease (IHD) continues to be the leading cause of cardiovascular mortality. Improvement of treatment methods is an important aspect in reduction of IHD fatal complications.Aim. To carry out a meta-analysis of several clinical and epidemiological studies with resea...

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The further development of preventive medicine in the 21st century may be impossible without the assessment of individual patients’ genetic data. At present, genetic methods are the gold standard in the diagnostics of monogenic diseases. Recently, genetic factors linked to complex (multifactorial) d...

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It is known that the common risk factors (RF) of cardiovascular diseases (CVD) do exist and do influence all people the same. Among them are arterial hypertension, smoking, total cholesterol, obesity etc. However there are specifics of RF realization connected to climatogeographic specifics, i.e. hi...

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Aim. As the endothelial glycocalix (EG) — gel-like layer on the surface of endothelium, participates in normal endothelial functioning maintenance, search for markers that characterize its condition, is of high scientific interest. Aim of the study — to evaluate clinical and diagnostic opportunities...

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Data of the World Health Organization and numerous clinical studies have shown a steady increase in the prevalence of obesity in the world. The number of obese people has doubled in the last three decades. The increase in obesity prevalence with age was found in Russia in the large epidemiological s...

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The main aim of the review is analysis of recent obesity classifications, taken from the viewpoint of cardiovascular diseases (CVD) risk stratification and metabolic diseases, evaluation of the complication risk and long-term prognosis (mortality). Novel obesity classification of AACE/ACE (2014) con...

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